Bone, growth & fractures

Osteogenesis Imperfecta

Brittle bone disease — and the HSS clinic Dr. Green directs.

Osteogenesis imperfecta (OI), often called brittle bone disease, is a genetic condition in which bone forms abnormally and breaks more easily than it should. It is lifelong, it varies enormously in severity between children, and it needs coordinated long-term care rather than treatment of one fracture at a time.

A gloved hand holding up a knee X-ray

A clinic, not a single appointment

Dr. Green has directed the Osteogenesis Imperfecta Clinic at the Hospital for Special Surgery since 2007. OI is one of the eight areas of special expertise he lists.

Children with OI are seen over years rather than episodes, and the orthopaedic care sits alongside the wider medical management of the condition.

How Dr. Green decides between surgery and non-surgical treatment

How Dr. Green treats osteogenesis imperfecta

  • Ongoing orthopaedic managementCare coordinated over time rather than fracture by fracture.
  • Surgical treatment where requiredOrthopaedic surgery as part of the overall management of the condition.
3 peer-reviewed papers on osteogenesis imperfecta

Dr. Green's published research on osteogenesis imperfecta

Of the papers indexed on PubMed under Dr. Green’s Hospital for Special Surgery affiliation, 3 are on this subject.

See the full publication record

Dr. Green wrote HSS’s clinical article on this condition

Osteogenesis Imperfecta (Brittle Bone Disease) appears in the HSS health library with Jessica H. Heyer, MD and Cathleen L. Raggio, MD. He is the first of 4 authors. The article is HSS’s, and it is published there rather than reproduced here.

Read it on hss.edu

The papers themselves

His 3 papers on this subject, indexed on PubMed under his Hospital for Special Surgery affiliation. Each opens on PubMed.

  1. Osteogenesis imperfecta: treatment and surgical management Current opinion in pediatrics · 2021 Feb 1 · Dr. Green is author 2 of 2
  2. Acetabular Protrusio in Patients With Osteogenesis Imperfecta: Risk Factors and Progression Journal of pediatric orthopedics · 2019 Nov/Dec · Dr. Green is author 4 of 4
  3. Acetabular Protrusio and Proximal Femur Fractures in Patients With Osteogenesis Imperfecta Journal of pediatric orthopedics · 2015 Sep · Dr. Green is author 5 of 5

Patients Dr. Green has treated for this condition

The Hospital for Special Surgery publishes these accounts in its Back in the Game archive. One lists Dr. Green as the treating surgeon. Each has its own page here, cited back to hss.edu.

Josie R Osteogenesis Imperfecta (Brittle Bone Disease) Josie R Woodhaven, NY Read Josie’s story
All 31 patient stories

Questions parents ask

What does the OI clinic at HSS do?

It provides coordinated orthopaedic care for children with osteogenesis imperfecta over the long term. Dr. Green has been its director since 2007.

Is osteogenesis imperfecta the same in every child?

No — OI varies widely in severity, which is why management is planned for the individual child.